History and Clinical Experience

• 1920's biological effects of high intensity ultrasound are demonstrated
• 1950's Indianapolis HIFU pioneer Fry studies Hifu for brain disorders
• 1970's Indianapolis early studies with use in prostate
• 2000's start of clinical usage of Hifu for prostate cancer and development of international sites for treatment of prostate cancer with the Sonablate 500 by USHIFU